WebDescription: Homo sapiens SIN3 transcription regulator family member A (SIN3A), transcript variant 3, mRNA. (from RefSeq NM_001145357) RefSeq Summary (NM_001145357): The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions … WebJun 1, 2024 · Data from clinical research and our previous study have suggested the potential involvement of SENP1, the major protease of post-translational SUMOylation, in cardiovascular disorders. Here, we ...
Thyroid hormone receptor alpha sumoylation modulates white …
WebBy examining both LC3-II induction and autophagosome formation with Mito-pHfluorin, we observed that while SENP3 knockdown blocks DFP-induced mitophagy, expression of “constitutively deSUMOylated” FIS1 K149R restores DFP-induced mitophagy in SENP3-lacking cells. Together, these results demonstrate that SENP3 promotes DFP-induced … WebDescription: Mus musculus dynamin 1-like (Dnm1l), transcript variant 2, mRNA. (from RefSeq NM_001025947) RefSeq Summary (NM_001025947): This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is … the preston group nyc
Human Gene SIN3A (ENST00000360439.8) from GENCODE V43
WebJul 20, 2024 · When BES1 is phosphorylated, whatever BES1 is sumoylated or desumoylated, the activity of BES1 is inhibited; once BES1 is dephosphorylated, the activity of BES1 is further activated by desumoylation. So BR signaling pathway regulates BR-response genes expression almost by dephosphorylating BES1/BZR1. And other … WebAug 23, 2024 · Thyroid hormone receptor β (THRB) is posttranslationally modified by small ubiquitin-like modifier (SUMO). We generated a mouse model with a mutation that … Websubunit, Rpc53, was desumoylated in all stresses with the exception of one nitrogen starvation biological replicate (Fig. 1C and Fig. S2) where it fell just below the cutoff. These data indicate that different stresses trigger stress-specific SSRs, and that RNAPIII subunits are desumoylated upon each stress tested here (also see below). sight and blindness in oedipus rex