Web雙相情緒障礙症分成 第一型雙相症 （英语：bipolar I disorder） 、 第二型雙相症 （英语：bipolar II disorder） 与环性心境障碍（Cyclothymic disorder），其症状大致相同，但表现形式差异较大。. 一型雙相情感障碍主要表现为抑郁与躁狂同时发作或于短时间内迅速交替 ... Hilary Kiyo Finucane is an American computational biologist who is Co-Director of the Program in Medical and Population Genetics at the Broad Institute. Her group combines genetic data with molecular data to understand the origins and mechanisms of disease.
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WebOct 17, 2024 · Fine-mapping aims to identify causal variants impacting complex traits. Several recent methods improve fine-mapping accuracy by prioritizing variants in enriched functional annotations. However, these methods can only use information at genome-wide significant loci (and/or a small number of functional annotations), severely limiting the … WebSep 28, 2015 · where N is sample size, C indexes categories, (j, C) is the LD score of SNP j with respect to category C (defined as ℓ (j, C) = ∑ k ∈ C r 2 j k ℓ (j, C) = ∑ k ∈ C r j k 2), a is a term that measures the contribution of confounding biases , and if the categories are disjoint, τ C is the per-SNP heritability in category C; if the ...
WebHilary K. Finucane's 191 research works with 23,907 citations and 18,703 reads, including: Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated … WebAug 22, 2024 · Meta-analysis is pervasively used to combine multiple genome-wide association studies (GWAS) into a more powerful whole. To resolve causal variants, meta-analysis studies typically apply summary statistics-based fine-mapping methods as they are applied to single-cohort studies. However, it is unclear whether heterogeneous …
WebDec 16, 2011 · Detecting Novel Associations in Large Data Sets David N. Reshef, Yakir A. Reshef , Hilary K. Finucane, Sharon R. Grossman, [...], and Pardis C. Sabeti +4 authors … WebHilary Finucane is an associated scientist in the Program in Medical and Population Genetics at the Broad Institute of MIT and Harvard and an …
WebRead Hilary K. Finucane's latest research, browse their coauthor's research, and play around with their algorithms. DeepAI.
WebHilary Finucane, PhD. Hilary Finucane is a Member of Faculty at Harvard Medical School and Massachusetts General Hospital and a Associate Member of the Genetics Program in the … how to talk on oculus quest 2WebHilary Kiyo Finucane is an American computational biologist who is Co-Director of the Program in Medical and Population Genetics at the Broad Institute. Her group combines … reagans lobster shop omahaWebJul 7, 2016 · Haplotype phasing is a fundamental problem in medical and population genetics. Phasing is generally performed via statistical phasing within a genotyped cohort, an approach that can attain high accuracy in very large cohorts but attains lower accuracy in smaller cohorts. Here, we instead explore the paradigm of reference-based phasing. We … reagans fitnessWebNov 21, 2024 · Here, we introduce the Global Biobank Meta-analysis Initiative (GBMI) -- a collaborative network of 19 biobanks from 4 continents representing more than 2.1 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWAS generated using harmonized genotypes and … how to talk slower when presentingWebFeb 18, 2024 · 1. It was allegedly a rebound relationship. Back in 2009, Flack was 29 and Harry was 25. Flack's star was just beginning to rise, as she'd gotten a gig as the host of … reagans last public appearanceWebSep 28, 2015 · Hilary K Finucane. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. Alexander Gusev, Po-Ru Loh & Alkes L Price. how to talk on the cb radioWebBrainstorm Consortium, Verneri Anttila, Brendan Bulik-Sullivan, Hilary K Finucane, Raymond K Walters, Jose Bras, Laramie Duncan, Valentina Escott-Price, Guido J Falcone, Padhraig Gormley, Rainer Malik, Nikolaos A Patsopoulos, Stephan Ripke, Zhi Wei, Dongmei Yu, Phil H Lee, Patrick Turley, Benjamin Grenier-Boley, Vincent Chouraki, Yoichiro Kamatani Show 31 … how to talk on the spot