Webb4 juni 2015 · The HIRAN domain was first identified as an evolutionarily conserved domain of unknown function, but its location within proteins containing DNA … WebbDownload scientific diagram Multiple alignment of the HIRAN domain. Proteins are represented by their gene names, species abbreviations and genbank index (gi) numbers separated by underscores ...
Identification of a Substrate Recognition Domain in …
WebbThe STING-mediated type I interferon (IFN) signaling pathway has been shown to play critical roles in antitumor immunity. Here, we demonstrate that an endoplasmic reticulum (ER)-localized JmjC domain-containing protein, JMJD8, inhibits STING-induced type I IFN responses to promote immune evasion and … Webb1 juni 2024 · The N-terminal HIRAN domain binds specifically to the 3′-end of single-stranded DNA (ssDNA), and disrupting this function interferes with fork regression in … mark and charli dwts
9761408 - Gene ResultThet_1625 HIRAN domain-containing protein []
Webb8 sep. 2015 · Alignment of the HIRAN domains present in various proteins (Figure 1B) revealed its highly conserved residues, and our model indicated that the HIRAN domain is a six-stranded β-barrel covered with a single α-helix at one end and either a short helix or a loop at the other end. WebbGene ID: 26637095, updated on 21-Dec-2024. Summary Other designations. putative HIRAN domain-containing protein Webb15 apr. 2024 · Protein target information for RUN and FYVE domain-containing protein 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. nausea and diarrhea causes