Impact of mirna in atherosclerosis

WitrynaAtherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the … WitrynaMoreover, miRNAs are present in peripheral blood with high stability and have the potential to be used as non-invasive biomarkers for the diagnosis of atherosclerosis. However, the circulating miRNA profile may vary according to the involved arterial territory, considering that atherosclerosis expression, including the associated …

MicroRNA Regulation of Atherosclerosis Circulation Research

Witryna1 wrz 2014 · Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of the common causes of cardiovascular morbidity and mortality, including myocardial infarction (MI), and cerebrovascular and peripheral vascular disease. Early pathological descriptions viewed atherosclerosis as an end-stage … Witryna9 maj 2024 · microRNAs (miRNAs) are implicated in the development of a wide range of diseases, including atherosclerosis, obesity, and diabetes (5–8).Among these miRNAs, aberrant let-7 expression is associated with diseases including liver and lung fibrosis and cancer (9,10).In the context of diabetes-associated atherosclerosis (DAA), previous … csptcl bhilai https://gcprop.net

The hub genes ranked by score as analyzed by Hubba plug-in.

Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. The Journal of clinical … Witryna17 gru 2024 · This study presents novel evidence linking miR-155 biology with the progression and regression of atherosclerosis. Herein, we have shown an inverse … Witryna21 kwi 2024 · MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance … eamonn mccrystal

Impact of miR-200b and miR-495 variants on the risk of large …

Category:MicroRNA expression profile of human advanced coronary

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Impact of mirna in atherosclerosis

The screened miR-342-5p facilitated the apoptosis of

WitrynaAtherosclerosis is a condition caused by lipid-induced inflammation of the vessel wall orchestrated by a complex interplay of various cell types, such as endothelial cells, smooth muscle cells, and macrophages. ... we outline the effects of miRNA-145, -126, and -155 in atherosclerosis in vivo. Downregulation of miR-145, which controls ... Witryna15 maj 2014 · The effect of miR-126-5p on atherosclerosis has been identified in vivo, which controls differentiation of smooth muscle cells, promotes lesion formation, whereas the endothelial cell-specific miR ...

Impact of mirna in atherosclerosis

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Witryna24 cze 2024 · The inhibition of miR-33 using pHLIP-directed macrophage targeting improves atherosclerosis regression by increasing collagen content and decreased … Witryna13 gru 2024 · Circulating MiRNAs as Potential Clinical Biomarkers for Atherosclerosis and CVD. Extensive research has revealed that miRNAs are extremely stable and …

WitrynaThis review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory response, insulin signaling and glucose/energy … Witryna19 sie 2024 · Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse functions. However, it remains a great challenge in clinical translation of nucleic acid‐based microRNA‐targeting therapeutics. …

Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, … WitrynaIt has been shown that several target genes of various miRNAs regulate platelet function and influence the interaction between circulating cells and vascular endothelium, both factors that can affect the process of cardiovascular diseases, such as atherosclerosis. MiRNAs, including miR-22, miR-185, and miR-320b, were seen to be upregulated in ...

WitrynaMaintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and vascular inflammation. Endothelial dysfunction is encompassed …

WitrynaBACKGROUND: Oxidative stress is a new risk factor for atherosclerosis. Increased oxidative stress in hemodialysis (HD) patients may arise from uremia-associated metabolic/humoral abnormalities and bi csptcl official websiteWitryna22 sie 2024 · Impact of miRNA in Atherosclerosis. miRNAs have received most of the attention during the last decades in particular for their role in tempering gene … eamonn mcgovernWitrynaDownload scientific diagram The enriched GO terms of twenty-five overlapped genes in atherosclerosis. from publication: Adipose-derived mesenchymal stem cells-derived … eamonn mckeownWitryna24 mar 2024 · Atherosclerosis (AS) is a chronic arterial disorder and a significant determinant of vascular death [].Fatty streaks in arterial walls regularly develop into characteristic plaques and atheroma [].The acute rupture of these atheromatous plaques leads to local thrombosis, causing partial or total occlusion of the affected artery [].AS … eamonn molloyWitryna11 lut 2024 · Importantly, various miRNAs can regulate the atherosclerosis process, such as miR-21. MiR-21 is the most abundant miRNA in macrophages and can regulate macrophage expression of inflammatory cytokines, such as IL-10 (48–50). Thus, modifying miR-21 in macrophage-derived exosomes has the potential to exert a … csptcl generationWitryna26 mar 2024 · Atherosclerosis has been recognized as an inflammatory disease involving the vascular wall. MicroRNAs are a group of small noncoding RNAs to … eamonn mcmahon swatraghWitrynaScience Volunteer eamonn mongey