WebLong term side effects. Naproxen can cause an ulcer in your stomach or gut if you take it for a long time. Your doctor may tell you not to take naproxen if you have a stomach ulcer or … WebDec 11, 2024 · Advil is made with a drug called ibuprofen while Aleve is made with the drug naproxen. Even though both are often taken for similar reasons, they have slightly different effects. Naproxen may remain active up to four times longer than ibuprofen. 1 This means you may have to take more ibuprofen for long-lasting relief, which can slightly ...
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